Actemra (Tocilizumab) Infusion Therapy
For the most detailed information, visit Actemra’s website.
Actemra® (tocilizumab) is an FDA-approved biologic medication given through an IV infusion. It works by blocking a protein called interleukin-6 (IL-6), which plays an important role in inflammation.
In conditions like rheumatoid arthritis, IL-6 can send signals that lead to inflammation, pain, and joint damage. Actemra helps quiet that signal, which may ease symptoms over time.
Moderate to severe rheumatoid arthritis (RA)
Giant cell arteritis (GCA)
Polyarticular juvenile idiopathic arthritis (PJIA)
Systemic juvenile idiopathic arthritis (SJIA)
Cytokine release syndrome (CRS) from CAR T-cell therapy
Systemic sclerosis–associated interstitial lung disease (SSc-ILD)
What Conditions Does Actemra Treat?
Your doctor may prescribe Actemra for one of these inflammatory or immune-related conditions:
What to Expect During Your Infusion

Before You Arrive
- Drink plenty of water in the days leading up to your appointment
- Eat a light meal unless your provider tells you otherwise
- Wear comfortable clothing with easy access to your arms
- Bring a book, tablet, or headphones to help pass the time
- Depending on how you feel after treatment, you may wish to arrange transportation home

During Your Appointment
Our team is here to make your experience as comfortable as possible.
- A nurse will review your medical information and answer questions
- Your arm will be cleaned and an IV line placed
- Your Actemra infusion will take about 60 minutes
- Your vital signs will be monitored during treatment
- Additional observation may be recommended based on medication protocols and your provider’s orders
How Often Will I Receive Actemra?
Most people receive Actemra every 2 to 4 weeks, depending on their condition. Each infusion takes about an hour.
| Infusion Duration | Typical Frequency |
| ~60 minutes | Every 2–4 weeks |
Common Side Effects
Like all medicines, Actemra may cause side effects. The most common ones reported during clinical studies include:
Notify your nurse or prescribing provider promptly if you experience concerning symptoms during or after treatment. This list is not exhaustive, please visit Actemra’s site for a complete list of side effects.
Upper respiratory infections (colds, sinus infections)
Headache
Higher blood pressure
Infusion-related reactions
How to Get Started

Your Provider Will Send
- Diagnosis and supporting records
- Previous treatment history
- Tuberculosis screening and lab results, if required
- Office information and provider signature
Every infusion requires a physician’s order.

You’ll Provide
- Your contact information
- Current insurance information
Once we receive your referral, our patient access team will begin insurance verification and prior authorization. We’ll work closely with your provider’s office and keep you informed throughout the process.

Why Choose Optimum Infusion?
Receiving infusion therapy shouldn’t add more stress to your life. Our goal is to make every visit comfortable and easy.
- Clear communication with your prescribing provider
- Comfortable infusion spaces with privacy dividers for a more personal experience
- Comfortable recliners with room for a guest
- Complimentary Wi-Fi and snacks
- Experienced infusion nurses focused on your care
- Insurance support and prior authorization assistance
- Convenient scheduling and free parking
- Wheelchair accessible
Ready to Schedule?
If you or your provider are interested in getting you infusion therapy at Optimum Infusion, we’re here to make the process easy.

Helpful Resources
- U.S. Food and Drug Administration. Actemra (tocilizumab) Prescribing Information.
Genentech, Inc. https://www.gene.com/download/pdf/actemra_prescribing.pdf - Genentech. ACTEMRA® (tocilizumab) — Dosing Schedule for Rheumatoid Arthritis. https://www.actemrahcp.com/ra/dosing-and-monitoring/dosing-schedule.html
This information is for general education and isn’t medical advice. Your prescribing provider decides whether a therapy is right for you. If you have questions about your treatment, talk with your provider.
