Entyvio (vedolizumab) Infusion Therapy
For the most detailed information, visit Entyvio’s website.
Entyvio® (vedolizumab) is an FDA-approved biologic infusion used to treat certain inflammatory bowel diseases. It works by targeting inflammation in the digestive tract, helping reduce symptoms while affecting the rest of the immune system less than some other biologic therapies.
At Optimum Infusion, we provide Entyvio infusions in a comfortable outpatient setting with experienced infusion nurses, personalized care, and seamless coordination with your prescribing provider.
Moderately to severely active ulcerative colitis (UC)
Moderately to severely active Crohn’s disease (CD)
What Conditions Does Entyvio Treat?
Entyvio is approved for adults with:
What to Expect During Your Infusion
Before You Arrive
- Drink plenty of water in the days leading up to your appointment
- Eat a light meal unless your provider tells you otherwise
- Wear comfortable clothing with easy access to your arms
- Bring a book, tablet, or headphones to help pass the time
- Depending on how you feel after treatment, you may wish to arrange transportation home
During Your Appointment
Our team is here to make your experience as comfortable as possible.
- A nurse will review your medical information and answer questions
- Your arm will be cleaned and an IV line placed
- Your Entyvio infusion will run for approximately 30 minutes
- Your vital signs will be monitored during treatment
- Additional observation may be recommended based on medication protocols and your provider’s orders
How Often Will I Receive Entyvio?
Your starter doses are at week 0, week 2, and week 6 — then you will move to maintenance infusions every 8 weeks. Each IV infusion takes about 30 minutes.
| Infusion Duration | Typical Frequency |
| ~30 minutes | Weeks 0, 2, and 6 (induction), then every 8 weeks (maintenance) |
Common Side Effects
The most common side effects of Entyvio include:
Notify your nurse or prescribing provider promptly if you experience concerning symptoms during or after treatment. This list is not exhaustive, please visit Entyvio’s website for a complete list of side effects.
Common cold symptoms
Headache
Joint pain
Nausea
Flu
Sinus or throat irritation
Tiredness
How to Get Started
Your Provider Will Send
- Diagnosis and supporting records
- Previous treatment history
- Confirmation that prior treatments were inadequate or not tolerated
- Office information and provider signature
Every infusion requires a physician’s order.
You’ll Provide
- Your contact information
- Current insurance information
Once we receive your referral, our patient access team will begin insurance verification and prior authorization. We’ll work closely with your provider’s office and keep you informed throughout the process.
Why Choose Optimum Infusion?
Receiving infusion therapy shouldn’t add more stress to your life. Our goal is to make every visit comfortable and easy.
- Clear communication with your prescribing provider
- Comfortable infusion spaces with privacy dividers for a more personal experience
- Comfortable recliners with room for a guest
- Complimentary Wi-Fi and snacks
- Experienced infusion nurses focused on your care
- Insurance support and prior authorization assistance
- Convenient scheduling and free parking
- Wheelchair accessible
Ready to Schedule?
If you or your provider are interested in getting you infusion therapy at Optimum Infusion, we’re here to make the process easy.
Helpful Resources
- U.S. Food and Drug Administration. Entyvio (vedolizumab) Prescribing Information. Takeda Pharmaceuticals. https://www.accessdata.fda.gov/drugsatfda_docs/label/2024/761133s005s006lbl.pdf
- Takeda Pharmaceuticals. ENTYVIO® (vedolizumab) for Crohn’s Disease or Ulcerative Colitis. https://www.entyvio.com/
- Takeda Pharmaceuticals. ENTYVIO® — Dosing and Administration (HCP). https://www.entyviohcp.com/dosing-administration
This information is for general education and isn’t medical advice. Your prescribing provider decides whether a therapy is right for you. If you have questions about your treatment, talk with your provider.