Orencia (Abatacept) Infusion Therapy
For the most detailed information, visit Orencia’s website.
Orencia® (abatacept) is an FDA-approved biologic medication given through an IV (intravenous) infusion to treat certain autoimmune conditions. It works by helping reduce the activity of T cells, a type of immune cell involved in inflammation. By targeting this part of the immune system, Orencia helps reduce inflammation that can damage joints and affect daily activities.
At Optimum Infusion, we provide Orencia infusion therapy in a comfortable outpatient setting with experienced infusion nurses, personalized care, and close communication with your rheumatologist throughout treatment.
Moderate to severe rheumatoid arthritis (RA) in adults
Active psoriatic arthritis (PsA) in adults
Polyarticular juvenile idiopathic arthritis (PJIA) in patients 6 years and older (IV form)
Prevention of acute graft-versus-host disease (aGVHD) in adults and children ≥2 years undergoing stem cell transplant
What Conditions Does Orencia Treat?
Orencia is approved for:
What to Expect During Your Infusion
Before You Arrive
- Drink plenty of water in the days leading up to your appointment
- Eat a light meal unless your provider tells you otherwise
- Wear comfortable clothing with easy access to your arms
- Bring a book, tablet, or headphones to help pass the time
- Depending on how you feel after treatment, you may wish to arrange transportation home
During Your Appointment
Our team is here to make your experience as comfortable as possible.
- A nurse will review your medical information and answer questions
- Your arm will be cleaned and an IV line placed
- Your Orencia infusion will run for approximately 30 minutes
- Your vital signs will be monitored during treatment
- Additional observation may be recommended based on medication protocols and your provider’s orders
How Often Will I Receive Orencia?
Your starting doses are given at week 0, week 2, and week 4, then you will switch to maintenance infusions every 4 weeks.
| Infusion Duration | Typical Frequency |
| ~30 minutes | Weeks 0, 2, and 4 (induction), then every 4 weeks (maintenance) |
Common Side Effects
The most common side effects reported with Orencia include:
Notify your nurse or prescribing provider promptly if you experience concerning symptoms during or after treatment. This list is not exhaustive, please visit Orencia’s site for a complete list of side effects.
Headache
Upper respiratory infection
Sore throat or stuffy nose
Nausea
How to Get Started
Your Provider Will Send
- Your diagnosis and supporting medical records
- Clinical documentation required by your insurance
- Provider information, including signature and NPI
Every infusion requires a physician’s order.
You’ll Provide
- Your contact information
- Current insurance information
Once we receive your referral, our patient access team will begin insurance verification and prior authorization. We’ll work closely with your provider’s office and keep you informed throughout the process.
Why Choose Optimum Infusion?
Receiving infusion therapy shouldn’t add more stress to your life. Our goal is to make every visit comfortable and easy.
- Clear communication with your prescribing provider
- Comfortable infusion spaces with privacy dividers for a more personal experience
- Comfortable recliners with room for a guest
- Complimentary Wi-Fi and snacks
- Experienced infusion nurses focused on your care
- Insurance support and prior authorization assistance
- Convenient scheduling and free parking
- Wheelchair accessible
Ready to Schedule?
If you or your provider are interested in getting you infusion therapy at Optimum Infusion, we’re here to make the process easy.
Helpful Resources
- U.S. Food and Drug Administration. Orencia (abatacept) Prescribing Information. Bristol Myers Squibb. https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/125118s240lbl.pdf
- Bristol Myers Squibb. ORENCIA® (abatacept) Patient Site. https://www.orencia.com/
- Bristol Myers Squibb. ORENCIA® — Intravenous Dosing for Moderate to Severe RA (HCP). https://www.orenciahcp.com/dosing-and-administration/intravenous.html
This information is for general education and isn’t medical advice. Your prescribing provider decides whether a therapy is right for you. If you have questions about your treatment, talk with your provider.