Tepezza (teprotumumab-trbw) Infusion Therapy
For the most detailed information, visit the official Tepezza website.
Tepezza® (teprotumumab-trbw) is an FDA-approved biologic medication given through an IV (intravenous) infusion to treat Thyroid Eye Disease (TED). It works by blocking a protein called the insulin-like growth factor-1 receptor (IGF-1R), which plays an important role in the inflammation and tissue changes that cause TED. By reducing this inflammation, Tepezza can help improve symptoms such as eye bulging, double vision, pain, and swelling.
At Optimum Infusion, we provide Tepezza infusion therapy in a comfortable outpatient setting with experienced infusion nurses, personalized care, and close communication with your ophthalmologist throughout treatment.

Thyroid Eye Disease (TED)
What Conditions Does Tepezza Treat?
Tepezza is FDA approved to treat adults with:
What to Expect During Your Infusion

Before You Arrive
- Drink plenty of water in the days leading up to your appointment
- Eat a light meal unless your provider tells you otherwise
- Wear comfortable clothing with easy access to your arms
- Bring a book, tablet, or headphones to help pass the time
- Depending on how you feel after treatment, you may wish to arrange transportation home

During Your Appointment
Our team is here to make your experience as comfortable as possible.
- A nurse will review your medical information and answer questions
- Your arm will be cleaned and an IV line placed
- Your Tepezza infusion will typically last 60 to 90 minutes, depending on which treatment you’re receiving
- Your vital signs will be monitored during treatment
- Additional observation may be recommended based on medication protocols and your provider’s orders
How Often Will I Receive Tepezza?
Tepezza is given as a series of 8 IV infusions.
| Infusion Duration | Typical Frequency |
| ~60-90 minutes | One infusion every 3 weeks for a total of 8 infusions |

Common Side Effects
Common side effects include:
Notify your nurse or prescribing provider promptly if you experience concerning symptoms during or after treatment. This list is not exhaustive, please visit Tepezza’s site for a complete list of side effects.
Muscle cramps or muscle spasms
Nausea
Hair thinning
Diarrhea
Fatigue
High blood sugar
Hearing changes
Changes in taste
Dry skin
How to Get Started

Your Provider Will Send
- Your diagnosis and supporting medical records
- Clinical documentation required by your insurance
- Recent laboratory results or other testing if required
- Provider information, including signature and NPI
Every infusion requires a physician’s order.

You’ll Provide
- Your contact information
- Current insurance information
Once we receive your referral, our patient access team will begin insurance verification and prior authorization. We’ll work closely with your provider’s office and keep you informed throughout the process.

Why Choose Optimum Infusion?
Receiving infusion therapy shouldn’t add more stress to your life. Our goal is to make every visit comfortable and easy.
- Clear communication with your prescribing provider
- Comfortable infusion spaces with privacy dividers for a more personal experience
- Comfortable recliners with room for a guest
- Complimentary Wi-Fi and snacks
- Experienced infusion nurses focused on your care
- Insurance support and prior authorization assistance
- Convenient scheduling and free parking
- Wheelchair accessible
Ready to Schedule?
If you or your provider are interested in getting you infusion therapy at Optimum Infusion, we’re here to make the process easy.

Helpful Resources
- U.S. Food and Drug Administration (FDA) – TEPEZZA® (teprotumumab-trbw) Prescribing Information
https://www.accessdata.fda.gov/drugsatfda_docs/label/2023/761143s016lbl.pdf - TEPEZZA® Official Patient Website
https://www.tepezza.com/ - TEPEZZA® Healthcare Professional (HCP) Dosing & Administration
https://www.tepezzahcp.com/dosing-and-administration
This information is for general education and isn’t medical advice. Your prescribing provider decides whether a therapy is right for you. If you have questions about your treatment, talk with your provider.
